Potential Risk Factors for Case Fatality Rate of Novel Coronavirus

Zhao, J., Li, X., Huang, W., and Zheng, J.. (2021). Potential Risk Factors for Case Fatality Rate of Novel Coronavirus (COVID-19) in China: A Pooled Analysis of Individual Patient Data. (Added 12/23/2020.) The American Journal of Emergency Medicine. 38(11):2374-2380.
Based on data from two cohort studies published by February 2020, the authors conducted a meta-analysis of risk factors for the case fatality rate (CFR) of COVID-19. They found the following factors associated with significantly increased CFR: age 60 and older (and even greater for 70 and older), male sex, retirees, and severe cases who received intensive care. They also found the CFR substantially decreased after January 21 due to improvements in early diagnosis and treatment.
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