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COVID-19 Vaccine Resources
Topic Collection
November 17, 2023

Topic Collection: COVID-19 Vaccine Resources

This Topic Collection focuses on vaccine-specific plans, tools, templates, and other immediately implementable resources to help with COVID-19 preparedness, response, recovery, and mitigation efforts.

The distribution and administration of vaccines to prevent COVID-19 should build on established plans. Federal, state, territorial, local, and tribal governments and their healthcare and other emergency preparedness partners have conducted extensive planning on the most effective methods to distribute and administer medical countermeasures – including vaccines – in their communities. Refer to the ASPR TRACIE Mass Distribution and Dispensing of Medical Countermeasures Topic Collection for related resources.  Resources marked with an asterisk (*) appear in more than one category.

This Resource Collection was reviewed in Fall 2023. Please refer to the NIH Coronavirus Disease 2019 (COVID-19) Treatment Guidelines and CDC’s Coronavirus Disease 2019 webpage for the most up-to-date guidance on COVID-19 outbreak management.

If you have COVID-19 best or promising practices, plans, tools, or templates to share with your peers, please visit the ASPR TRACIE Information Exchange COVID-19 Information Sharing Page (registration required) and place your resources under the relevant topic area. Resources specific to Vaccines can be placed under the COVID-19 Vaccines Resources Topic.

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Education and Training

American Medical Association. (2023). COVID-19 and Vaccine Development. (Added 12/28/2020.)
This page includes links to webinars and other educational information related to COVID-19 vaccination.
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* Centers for Disease Control and Prevention. (2023). COVID-19 Vaccination. (Added 2/10/2021.) U.S. Department of Health and Human Services.
This page provides links to training and educational materials related to immunization practices. It also includes COVID-19 vaccine-specific information.
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Centers for Disease Control and Prevention. (2023). COVID-19 Vaccine Training Module. (Added 12/28/2020.) U.S. Department of Health and Human Services.
This online training module provides information to healthcare workers on COVID-19 vaccine approval and safety, storage, handling, administration, and reporting.
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* COVID-19 Real-Time Learning Network. (2023). Vaccines and Immunity. (Added 12/23/2020.) Centers for Disease Control and Prevention and Infectious Diseases Society of America.
This page provides a broad range of information on vaccine development and distribution planning.
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* Immunization Action Coalition. (2020). Skills Checklist for Vaccine Administration. (Added 2/10/2021.)
This checklist is a self-assessment tool developed for healthcare staff who administer immunizations. Supervisors can also use this tool to identify roles and responsibilities for staff who administer vaccines.
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TRAIN. (2020). COVID-19 Vaccination Training Programs for Healthcare Professionals. (Added 12/28/2020.) (Free registration required.)
This page offers links to vaccination training programs for health professionals.
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General Resources

ASPR TRACIE. (2018). Mass Distribution and Dispensing of Medical Countermeasures.
This Topic Collection provides links to federal, state, local, and tribal programs and resources, lessons learned, plans, tools, and templates, courses, and guidance that can help planners address the need to effectively distribute and administer medical countermeasures (MCMs) to a large number of persons in a short period of time, particularly through mass dispensing efforts led by public health authorities.
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ASPR TRACIE. (2020). Influenza Epidemic/ Pandemic. U.S. Department of Health and Human Services, Office of the Assistant Secretary of Preparedness and Response.
The resources in this Topic Collection include the lessons learned from the 2009 pandemic, strategies for maintaining “business as usual” for healthcare facilities, checklists, and others that can help emergency medical staff plan for and respond to a pandemic.
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Centers for Disease Control and Prevention. (2021). COVID-19 ACIP Vaccine Recommendations. (Added 8/24/2021.) U.S. Department of Health and Human Services.
This page lists all recommendations by the Advisory Committee on Immunization Practices related to the COVID-19 vaccine.
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Centers for Disease Control and Prevention. (2023). COVID-19 Vaccine Effectiveness and Safety. (Added 8/24/2021.) U.S. Department of Health and Human Services.
This page lists all reports published in the Morbidity and Mortality Weekly Report related to the safety and effectiveness of COVID-19 vaccines.
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* COVID-19 Real-Time Learning Network. (2023). Vaccines and Immunity. (Added 12/23/2020.) Centers for Disease Control and Prevention and Infectious Diseases Society of America.
This page provides a broad range of information on vaccine development and distribution planning.
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* U.S. Food and Drug Administration. (2020). Vaccine Development – 101. (Added 12/23/2020.) U.S. Department of Health and Human Services.
This webpage describes the steps that vaccine developers follow when seeking FDA approval of a vaccine.
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U.S. Food and Drug Administration. (2023). COVID-19 Vaccines. (Added 12/23/2020.) U.S. Department of Health and Human Services.
This landing page provides links to the latest information on the development and approval of COVID-19 vaccines.
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Plans, Tools, and Templates

AABB. (2022). Toolkit for COVID-19 Convalescent Plasma (CCP) under Emergency Use Authorization (EUA). (Added 1/11/2021.)
This frequently updated toolkit includes tabulated information about changes to the Emergency Use Authorization (EUA) for COVID-19 Convalescent Plasma (CCP); detailed information about blood donor referrals after COVID-19 vaccination or CCP infusion; flowcharts on investigational and EUA use, collection, and testing and labeling of CCP, and a sample flowchart for updating a deferral policy for vaccines to help evaluate donor risk following vaccination.
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American Society of Health-System Pharmacists. (2020). ASHP COVID-19 Vaccine Planning Tool for Pharmacists and Pharmacies.
This tool can assist with the involvement of pharmacists and pharmacy staff in institutional and community COVID-19 vaccine planning efforts. It addresses integration with facility planning, vaccine supply and distribution, infrastructure, personnel, patient care, vaccine safety monitoring and surveillance, and legislative and regulatory controls.
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ASPR TRACIE. (2021). Mass Vaccination Plans.
This ASPR TRACIE TA response includes mass vaccination plans to support COVID-19 vaccine administration efforts.
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* Association of Immunization Managers. (2021). Vaccine Confidence Toolkit.
This resource page includes links to various materials to help communicate about COVID-19 vaccination.
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* Centers for Disease Control and Prevention. (2020). Checklist of Best Practices for Vaccination Clinics Held at Satellite, Temporary, or Off-Site Locations. (Added 2/10/2021.) U.S. Department of Health and Human Services.
This checklist provides step-by-step guidance for clinic coordinators/supervisors who oversee vaccination clinics held at satellite, temporary, or offsite locations. It includes guidelines and best practices, as set forth by the Centers for Disease Control and Prevention (CDC), as it pertains to vaccine shipment, transport, storage, handling, preparation, administration, and documentation.
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* Centers for Disease Control and Prevention. (2023). Vaccine Storage and Handling Toolkit. (Added 12/23/2020.) U.S. Department of Health and Human Services.
This toolkit shares best practices for vaccine storage and handling. It includes an addendum focused on COVID-19 and Mpox vaccines.
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* Federal Emergency Management Agency. Office of Equal Rights. (2021). FEMA Advisory: Civil Rights Considerations During COVID-19 Vaccine Distribution Efforts. (Added 3/25/2021.) U.S. Department of Homeland Security.
This checklist offers federal, state, local, and tribal authorities elements to ponder in the categories of inclusive planning, effective communication access, language access, and physical accessibility, as they plan equitable vaccine distribution in their communities.
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Post-Vaccination Issues

American Society of Hematology. (2022). Vaccine-induced Immune Thrombotic Thrombocytopenia: Frequently Asked Questions. (Added 4/16/2021.)
These frequently asked questions - expected to be updated as additional information becomes available - provide details about the diagnosis and treatment of vaccine-induced thrombotic thrombocytopenia (VITT) occurring following COVID-19 vaccination.
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CDC COVID-19 Response Team and U.S. Food and Drug Administration. (2021). Allergic Reactions Including Anaphylaxis After Receipt of the First Dose of Moderna COVID-19 Vaccine - United States, December 21, 2020-January 10, 2021. (Added 1/25/2021.) Morbidity and Mortality Weekly Report. 70..
This report documents initial reports of adverse events following administration of the first dose of the Moderna COVID-19 vaccine. Between December 21, 2020 and January 10, 2021, 10 cases of anaphylaxis were reported following administration of 4,041,396 first doses of the vaccine.
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CDC COVID-19 Response Team and U.S. Food and Drug Administration. (2021). Allergic Reactions Including Anaphylaxis After Receipt of the First Dose of Pfizer-BioNTech COVID-19 Vaccine — United States, December 14–23, 2020. (Added 1/11/2021.) Morbidity and Mortality Weekly Report. 70..
This report details initial reports of adverse events following administration of the first dose of the Pfizer-BioNTech vaccine. Between December 14 and 23, 2020, 21 cases of anaphylaxis were reported following administration of 1,893,360 doses of vaccine.
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Centers for Disease Control and Prevention. (2020). V-safe After Vaccination Health Checker. (Added 12/28/2020.) U.S. Department of Health and Human Services.
This page includes information about the smartphone-based tool for personalized check-ins following vaccination to prevent COVID-19. The page offers a description of the tool and registration information.
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Centers for Disease Control and Prevention. (2021). Clinical Considerations: Myocarditis and Pericarditis after Receipt of mRNA COVID-19 Vaccines Among Adolescents and Young Adults. U.S. Department of Health and Human Services.
This resource page provides recommendations for clinicians related to reports of myocarditis and pericarditis in adolescents and young adults following mRNA COVID-19 vaccination.
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Risk Communication Tools and Considerations

#Get Vaccinated. (2023). Provider Resources. (Added 12/28/2020.) American Health Care Association and National Center for Assisted Living .
This toolkit contains various resources to support the #GetVaccinated campaign, including talking points, templates, and media materials.
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American Pharmacists Association. (2021). Vaccine Hesitancy: Understanding and Addressing Vaccine Hesitancy During COVID-19. (Added 1/11/2021.)
This updated fact sheet provides information for pharmacists’ conversations with their customers about immunization, including tips for addressing vaccine hesitancy generally and in racial or ethnic minority populations more specifically.
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ASPR TRACIE. (2021). Be a COVID-19 Vaccine Champion Webinar.
The speakers discuss the campaign designed to build confidence in and address hesitancy related to COVID-19 vaccines.
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* Association of Immunization Managers. (2021). Vaccine Confidence Toolkit.
This resource page includes links to various materials to help communicate about COVID-19 vaccination.
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Centers for Disease Control and Prevention. (2020). U.S. COVID-19 Vaccine Product Information. (Added 12/28/2020.) U.S. Department of Health and Human Services.
This page offers suggestions for healthcare providers on answering patient questions about vaccination to prevent COVID-19.
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Centers for Disease Control and Prevention. (2020). Vaccine Recipient Education. (Added 12/28/2020.) U.S. Department of Health and Human Services.
This page offers communication strategies to aid healthcare providers in talking with their patients about vaccination to prevent COVID-19.
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Centers for Disease Control and Prevention. (2020). Vaccines. (Added 12/28/2020.) U.S. Department of Health and Human Services.
This landing page provides information for the public about COVID-19 vaccines, recommendations, administration plans, and safety. It also includes answers to frequently asked questions.
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Chou, W., Burgdorf, C., Gaysynsky, A., and Hunter, C.. (2021). COVID-19 Vaccination Communication: Applying Behavioral and Social Science to Address Vaccine Hesitancy and Foster Vaccine Confidence. (Added 3/25/2021.) National Institutes of Health.
The authors describe foundational communication elements and specific objectives for federal agency vaccine communications, along with those of their state and local partners, broken down by audience groups. It includes an extensive list of hyperlinked references.
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Gonzales, A., Lee, E., Grigorescu, V., et al. (2021). Overview of Barriers and Facilitators in COVID-19 Vaccine Outreach. (Added 10/8/2021) U.S. Department of Health and Human Services, Office of the Assistant Secretary for Planning and Evaluation.
This report shares lessons learned, describes COVID-19 vaccine outreach evidence, and offers examples of successful vaccination outreach strategies.
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Lin, C., Tu, P., and Beitsch, L. (2021). Confidence and Receptivity for COVID-19 Vaccines: A Rapid Systematic Review. (Added 1/11/2021.) Vaccines. 9(1):16..
This article includes one flow diagram of the study’s search and selection process and three charts illustrating data about vaccine hesitancy as reported in 126 studies and surveys, selected from searches of academic literature, news, and official reports that were published by October 20, 2020.
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National Resource Center for Refugees, Immigrants, and Migrants (NRC-RIM). (2022). Vaccine Central. University of Minnesota.
This webpage includes various resources for vaccine providers working with refugee, immigrant, and migrant communities to increase COVID-19 vaccination rates.
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New York City Health + Hospitals. (2021). Be a COVID19 Vaccine Champion Toolkit. (Added 5/13/2021.)
This toolkit includes: a manual providing a summary of what clinicians need to know about COVID-19 vaccines and how to communicate with patients about them; a guide to learning about COVID-19 vaccines; a PowerPoint template for hosting a webinar or lecture; audience poll questions; and instructions on how to use the documents.
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Public Health Institute. (2020). Communicating about the COVID-19 Vaccines: Guidance and Sample Messages for Public Health Practitioners. (Added 12/28/2020.)
This page provides tips and sample language for communicating with the public about COVID-19 vaccination.
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Schoch-Spana, M., Brunson, E., Long, R., et al. (2021). The Public’s Role in COVID-19 Vaccination: Human-Centered Recommendations to Enhance Pandemic Vaccine Awareness, Access, and Acceptance in the United States. Vaccine. 39(40):6004-6012.
The authors – members of the Working Group on Readying Populations for COVID-19 Vaccines – offer six recommendations to advance public understanding of, access to, and acceptance of COVID-19 vaccines.
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Trust for America’s Health. (2020). Ensuring COVID-19 Vaccine Access, Safety, and Utilization: Building Vaccination Confidence in Communities of Color. (Added 12/28/2020.)
This webinar offers suggestions on how to build vaccine confidence and access in communities of color.
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We Can Do This. (2022). COVID-19 Public Education Campaign. U.S. Department of Health and Human Services.
This page includes links to videos, social media messages, posters and flyers, and other informational content to help clinicians educate patients on the importance of up-to-date COVID-19 vaccination.
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World Health Organization. (2021). Tackling COVID-19 Misinformation: A Social Media Toolkit for Healthcare Practitioners.
This toolkit provides messages and techniques that healthcare practitioners may use to increase vaccine confidence among their patients. Users may download desktop or mobile versions of the toolkit.
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Vaccine Allocation and Equity

Emanuel, E., Persad, G., Kern, A., et al.. (2020). An Ethical Framework for Global Vaccine Allocation. (Added 12/28/2020.) Science. 369(6509):1309-1312.
The authors of this article describe a three-phased Fair Priority Model for distribution of COVID-19 vaccine that prioritizes preventing urgent harms earlier. Phase 1 addresses premature deaths and other irreversible health effects, phase 2 addresses other enduring health harms and economic and social deprivations, and phase 3 addresses community transmission.
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* Federal Emergency Management Agency. Office of Equal Rights. (2021). FEMA Advisory: Civil Rights Considerations During COVID-19 Vaccine Distribution Efforts. (Added 3/25/2021.) U.S. Department of Homeland Security.
This checklist offers federal, state, local, and tribal authorities elements to ponder in the categories of inclusive planning, effective communication access, language access, and physical accessibility, as they plan equitable vaccine distribution in their communities.
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The National Academies of Sciences, Engineering, and Medicine. (2020). Framework for Equitable Allocation of COVID-19 Vaccine. The National Academies Press.
This consensus study report offers a phased framework based on ethical and procedural principles for equitable allocation of COVID-19 vaccine that reduces severe morbidity and mortality and negative societal effects of the pandemic. In addition to the framework, the authors addressed implementation challenges related to program administration, risk communication and community engagement, vaccine acceptance, and global equity in allocation.
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Vaccine Development and Approval

U.S. Food and Drug Administration. (2020). Emergency Use Authorization for Vaccines to Prevent COVID-19. (Added 12/30/2020.) U.S. Department of Health and Human Services.
This guidance document assists sponsors in understanding the data and information required to support the issuance of an emergency use authorization for a vaccine to prevent COVID-19.
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U.S. Food and Drug Administration. (2020). The Path for a COVID-19 Vaccine from Research to Emergency Use Authorization. (Added 12/30/2020.) U.S. Department of Health and Human Services.
This graphic illustrates the key steps in the COVID-19 vaccine approval process.
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* U.S. Food and Drug Administration. (2020). Vaccine Development – 101. (Added 12/23/2020.) U.S. Department of Health and Human Services.
This webpage describes the steps that vaccine developers follow when seeking FDA approval of a vaccine.
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U.S. Food and Drug Administration. (2023). Development and Licensure of Vaccines to Prevent COVID-19. (Added 12/30/2020.) U.S. Department of Health and Human Services.
This guidance document assists sponsors in the clinical development and licensure of vaccines to prevent COVID-19.
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Vaccine Logistics - Administration

Agency for Healthcare Research and Quality. (2021). Invest in Trust: A Guide for Building COVID-19 Vaccine Trust and Increasing Vaccination Rates Among CNAs. (Added 10/7/2021) U.S. Department of Health and Human Services.
This guide is intended to help nursing home administrators build trust in vaccines among their certified nursing assistants and overcome barriers to vaccination.
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American Medical Association. (2020). COVID-19 CPT Vaccine and Immunization Codes. (Added 12/30/2020.)
This page is a reference for the Current Procedural Terminology code set for COVID-19 vaccine-specific codes.
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ASPR TRACIE. (2020). Hospital Operations Toolkit for COVID-19: Administration – Vaccine Logistics.
This section of the Hospital Operations Toolkit for COVID-19 discusses strategies for hospitals to administer allocated vaccine to their staff.
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ASPR TRACIE. (2021). Vaccination Clinic Resources.
This ASPR TRACIE TA response provides resources, such as checklists, tailored towards bringing external volunteers onboard at a public-facing vaccination clinic.
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ASPR TRACIE. (2023). COVID-19 Vaccination Quick Links.
ASPR TRACIE created this list to assist clinicians in quickly finding the most relevant and current information about COVID-19 vaccines available in the United States, their intended populations, recommendations for their use, effectiveness and safety issues, potential adverse events to be aware of, the effects of SAR-COV-2 variants on the vaccinated, and resources to help communicate with patients. Additional resources are also listed to access more detailed information.
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* Centers for Disease Control and Prevention. (2020). Checklist of Best Practices for Vaccination Clinics Held at Satellite, Temporary, or Off-Site Locations. (Added 2/10/2021.) U.S. Department of Health and Human Services.
This checklist provides step-by-step guidance for clinic coordinators/supervisors who oversee vaccination clinics held at satellite, temporary, or offsite locations. It includes guidelines and best practices, as set forth by the Centers for Disease Control and Prevention (CDC), as it pertains to vaccine shipment, transport, storage, handling, preparation, administration, and documentation.
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Centers for Disease Control and Prevention. (2020). Considerations for Planning Curbside/Drive-Through Vaccination Clinics. U.S. Department of Health and Human Services.
This resource page provides information for those planning curbside or drive-through vaccination clinics. It offers steps for planning the clinic and what to do before, during, and after the vaccination encounter. It also includes links to additional resources.
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Centers for Disease Control and Prevention. (2021). Strategies for Sharps Disposal Container Use During Supply Shortages.
The information on this page can help COVID-19 vaccinators and others assisting at COVID-19 mass vaccination sites reduce needlestick injuries and exposures.
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* Centers for Disease Control and Prevention. (2023). COVID-19 Vaccination. (Added 2/10/2021.) U.S. Department of Health and Human Services.
This page provides links to training and educational materials related to immunization practices. It also includes COVID-19 vaccine-specific information.
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* Centers for Disease Control and Prevention. (2023). Vaccine Storage and Handling Toolkit. (Added 12/23/2020.) U.S. Department of Health and Human Services.
This toolkit shares best practices for vaccine storage and handling. It includes an addendum focused on COVID-19 and Mpox vaccines.
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Centers for Medicare & Medicaid Services. (2020). COVID-19 Vaccine Policies and Guidance. (Added 12/30/2020.) U.S. Department of Health and Human Services.
This page links to toolkits on COVID-19 vaccine enrollment, coverage, reimbursement, and other information for healthcare providers, state Medicaid programs and Children’s Health Insurance Programs, health insurers, and those helping consumers and beneficiaries.
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* Cybersecurity and Infrastructure Security Agency. (2020). Primer on Safe and Efficient Handling of Dry Ice. (Added 12/30/2020.) U.S. Department of Homeland Security.
This document provides handling information for owners and operators related to dry ice.
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Health Resources and Services Administration. (2021). COVID-19 Vaccine Booster Planning Checklist. (Added 10/7/2021) U.S. Department of Health and Human Services.
This planning checklist is intended to help health centers assess their readiness to administer COVID-19 vaccine boosters.
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* Immunization Action Coalition. (2020). Skills Checklist for Vaccine Administration. (Added 2/10/2021.)
This checklist is a self-assessment tool developed for healthcare staff who administer immunizations. Supervisors can also use this tool to identify roles and responsibilities for staff who administer vaccines.
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The American College of Obstetricians and Gynecologists. (2023). Vaccinating Pregnant and Lactating Patients Against COVID-19. (Added 12/30/2020.)
This practice advisory reviews the available evidence related to COVID-19 vaccination in pregnant and lactating patients and offers recommendations to guide conversations between providers and their patients about whether to be vaccinated.
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Vaccine Logistics - Distribution

Cybersecurity and Infrastructure Security Agency. (2020). Cold Storage Cyber Custodial Care. (Added 12/30/2020.) U.S. Department of Homeland Security.
This document offers recommendations to owners and operators of cold storage facilities to prepare for cyber threats.
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Cybersecurity and Infrastructure Security Agency. (2020). Critical Questions and Considerations for Cold Chain, Storage, and Dry Ice Operations. (Added 12/30/2020.) U.S. Department of Homeland Security.
This list of questions is intended to inform considerations of state, local, territorial, and tribal governments, private sector entities, and cold storage facility owners and operators related to physical security, cyber and infrastructure resiliency, personnel security, and incident response capabilities associated with COVID-19 vaccination logistics.
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Cybersecurity and Infrastructure Security Agency. (2020). Physical Security for Cold Storage Locations. (Added 12/30/2020.) U.S. Department of Homeland Security.
This document outlines considerations for the security and integrity of facilities that receive, house, and distribute COVID-19 vaccine.
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* Cybersecurity and Infrastructure Security Agency. (2020). Primer on Safe and Efficient Handling of Dry Ice. (Added 12/30/2020.) U.S. Department of Homeland Security.
This document provides handling information for owners and operators related to dry ice.
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