Prophylactic Antibiotics for Burns Patients Systematic Review and Meta-Analysis

The authors performed a review and meta-analysis of studies that looked at the use of systemic antibiotics in burn patients. They found a benefit in all-cause mortality at 100 days to prophylactic antibiotics, but note the poor quality of the research to that point in time, so only recommend perioperative use of antibiotics. While the article is dated, experts continue to agree that prophylaxis is not recommended.