Kraft, R., Herndon, D.N., Finnerty, C.C., et al. (2014). Occurrence of Multiorgan Dysfunction in Pediatric Burn Patients: Incidence and Clinical Outcome. Annals of Surgery. 259(2):381-7.
This prospective study of 821 pediatric burn patients with burns over greater than 30% of their bodies at a single burn center categorized patients as having single- organ failure, multi-organ failure, and no organ failure, and related impact on clinical outcomes. The authors found that patients with liver and renal failure had the worst outcomes, while those with cardiac and pulmonary organ failures had good prognoses. Patients with three or more organ failures were generally fatal cases.