Assessing the State of Knowledge Regarding the Effectiveness of Interventions to Contain Pandemic Influenza Transmission A Systematic Review and Narr

This study reviews existing systematic reviews and meta-analyses on pandemic influenza interventions including vaccines, antivirals, personal protective measures, school closures, and traditional Chinese medicine. Pandemic influenza vaccine was found to be protective against infection, but the authors found insufficient evidence for the effectiveness of each of the other interventions in isolation and hypothesized that a combination of interventions would be most effective.