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Influenza in Infants Born to Women Vaccinated During Pregnancy

Shakib, J., Korgenski, K., Presson, A., et al. (2017). Influenza in Infants Born to Women Vaccinated During Pregnancy. Pediatrics. 137(6).

This cohort study to compare influenza outcomes of infants less than 6 months of age born to vaccinated and unvaccinated women included more than 245,000 women who delivered nearly 250,000 infants in a single health system between December 2005 and March 2014. The authors found that while only 10% of pregnant women were vaccinated during the overall course of the study, the proportion steadily increased to 52% in the final season. They also found a 64% reduction in influenza-like illness health encounters, a 70% reduction in laboratory-confirmed influenza, and an 81% reduction in hospitalization with laboratory-confirmed influenza in infants born to women who reported being vaccinated during pregnancy and 97% of laboratory-confirmed influenza in infants less than 6 month occurred in those born to women who did not report being vaccinated during pregnancy.
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