Saunders-Hastings, P., Quinn Hayes, B., Smith, R., and Krewski, D. (2017). Modelling Community-Control Strategies to Protect Hospital Resources During An Influenza Pandemic in Ottawa, Canada. PLoS One. 12(6).
The authors modeled the effects on hospital capacity in one city of various strategies to control an influenza pandemic. They calculated ranges bounded by no interventions and all interventions for the attack rate, peak acute care hospital capacity, peak intensive care unit capacity, and mortality along with estimated economic burdens. They found vaccination, isolation, and personal protective measures to be the most effective strategies. However, all interventions decreased in effectiveness as transmissibility increased and as the outbreak progressed.