Buckley, N., Eddleston, M., and Szinicz, L. (2005). Oximes for Acute Organophosphate Pesticide Poisoning. (Abstract only.) The Cochrane Database of Systemic Reviews. 25(1).
While the traditional treatment for this type of poisoning has been intravenous atropine and oxime (e.g., pralidoxime and obidoxime), the practicality of oximes has been disputed by physicians across the globe. Based on literature reviews, the authors conclude there is not enough evidence either way and emphasize the need for further research.