Mitchell, K.B., Khalil, E., Brennan, A., et al. (2013). New Management Strategy for Fluid Resuscitation: Quantifying Volume in the First 48 Hours after Burn Injury. Journal of Burn Care Research. 34(1):196-202.
The authors prospectively collected data on 40 patients with burns =15% from 2009-2011 to evaluate a 24-hour resuscitation protocol; establish a formula to quantify resuscitation volume for the second 24 hours (provided in the article); describe the relationship between the first and second 24 hours; and, identify which patients required high volumes. They found that intubation, higher age, and use of narcotics increased fluid needs and that there is a correlation between the first and second 24 hours.