Long-Term Persistance of the Pathophysiologic Response to Severe Burn Injury

This cohort study was conducted from 1998-2008, and enrolled 997 pediatric burn patients and a matched control group to measure hypermetabolic and inflammatory changes for 36 months post-burn. The authors found that alterations persisted for far longer than originally thought, and that severely burned pediatric patients require treatment for a longer period of time.