Kraft, R., Herndon, D.N., Branski, L.K., et al. (2013). Optimized Fluid Management Improves Outcomes of Pediatric Burn Patients. Journal of Surgical Research. 181(1):121-8.
The authors compared results of fluid resuscitation using a transcardiopulmonary thermo-dilution monitoring device (PiCCO) vs. fluid resuscitation using body weight, burn size, and urinary output in pediatric patients with burns over greater than 30% of their bodies. There were 76 patients in each group. Patients were followed for 20 days post-burn and there was less incidence of cardiac and renal failure in the PiCCO group.