Association of Prehospital Plasma Transfusion with Survival in Trauma Patients with Hemorrhagic Shock When Transport Times Are Longer Than 20 Minutes

Pusateri, A., Moore, E., Moore, H., et al. (2020). Association of Prehospital Plasma Transfusion with Survival in Trauma Patients with Hemorrhagic Shock When Transport Times Are Longer Than 20 Minutes. JAMA Surgery. 155(2):e195085.
The authors randomly assigned 626 patients in hemorrhagic shock after trauma to receive either standard pre-hospital care or two units of thawed plasma. They found that during emergency medical services transport times longer than 20 minutes, plasma transfusion before arrival at the hospital significantly reduced 28-day mortality.
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