Use of Cold-Stored Whole Blood is Associated with Improved Mortality in Hemostatic Resuscitation of Major Bleeding A Multicenter Study

Hazelton, J., Ssentongo, A., Oh, J., et al. (2022). Use of Cold-Stored Whole Blood is Associated with Improved Mortality in Hemostatic Resuscitation of Major Bleeding: A Multicenter Study. Annals of Surgery. 276(4):579-588.
The authors conducted a prospective, observational study to understand how whole blood versus blood component therapy affected patient outcomes in bleeding trauma patients. They found that compared with blood component therapy, whole blood was associated with a 48% reduction in mortality for these patients.
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