Oxygen Consumption with High-Flow Nasal Oxygen versus Mechanical Ventilation- An International Multicenter Observational Study in COVID-19 Patients

The authors compared the amount of supplemental oxygen consumed with high-flow nasal oxygen versus mechanical ventilation during the first two full days of oxygen support in the intensive care unit of patients enrolled in a larger observational study of patients with hypoxemic respiratory failure due to COVID-19. They calculated actual, hourly, and daily data on consumption to inform hospital planning for oxygen needs and conservation strategies.