Ebolavirus Diagnosis Made Simple Comparable and Faster than Molecular Detection Methods Preparing for the Future
James, A., Todd, S., Pollak, N., et al. (2018). Ebolavirus Diagnosis Made Simple, Comparable and Faster than Molecular Detection Methods: Preparing for the Future. Virology Journal. 15(75).
The authors developed a rapid assay for detection of Ebola using recombinase polymerase amplification. They found their assay to be comparable to RT-PCR-based assays, with the same detection limit as PCR and highly specific for Ebola Zaire. They suggest the assay could be useful in low-resource settings lacking capacity for RT-PCR.